SREBF1
sterol regulatory element binding transcription factor 1
동의어:
SREBP-1c, SREBP1, bHLHd1
종:
Human SREBF1 (6720), Mouse Srebf1 (20787), Rat Srebf1 (78968), chicken SREBF1 (373915), domestic cat SREBF1 (101087535), dog SREBF1 (403475), Horse SREBF1 (100052283), sheep SREBF1 (100329218), Goat SREBF1 (100860908), cow SREBF1 (539361) ...더
UniProtKB ID:
Clone ID:
- Human(6720) Summary: This gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(20787) sterol regulatory element binding transcription factor 1
- Rat(78968) sterol regulatory element binding transcription factor 1
- chicken(373915) sterol regulatory element binding transcription factor 1
- domestic cat(101087535) sterol regulatory element binding transcription factor 1
- dog(403475) sterol regulatory element binding transcription factor 1
- Horse(100052283) sterol regulatory element binding transcription factor 1
- sheep(100329218) sterol regulatory element binding transcription factor 1
- Goat(100860908) sterol regulatory element binding transcription factor 1
- cow(539361) sterol regulatory element binding transcription factor 1
- domestic guinea pig(100731641) sterol regulatory element binding transcription factor 1
- naked mole-rat(101705277) sterol regulatory element binding transcription factor 1
- Zebrafish(793274) sterol regulatory element binding transcription factor 1
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-SREBF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-phospho-SREBP-1 (pSer439) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
western blot
Anti-SREBP-1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, rat
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SREBF1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, goat, guinea pig, horse, human, mouse, rabbit, rat
응용분야
western blot
Anti-SREBF1 (AB1) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
western blot