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Merck

SRD5A3

steroid 5 alpha-reductase 3

동의어:
CDG1P, CDG1Q, KRIZI, SRD5A2L, SRD5A2L1
:
UniProtKB ID:
Clone ID:
  • Human(79644) Summary: The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]
  • Mouse(57357) steroid 5 alpha-reductase 3
  • Rat(305291) steroid 5 alpha-reductase 3
  • chicken(422750) steroid 5 alpha-reductase 3
  • cow(535834) steroid 5 alpha-reductase 3
  • sheep(101106772) steroid 5 alpha-reductase 3
  • dog(482155) steroid 5 alpha-reductase 3
  • domestic cat(101090010) steroid 5 alpha-reductase 3
  • domestic guinea pig(100727041) steroid 5 alpha-reductase 3
  • naked mole-rat(101726767) steroid 5 alpha-reductase 3
  • Zebrafish(560717) steroid 5 alpha-reductase 3

Custom & Knockdown Gene Products

Small Molecule - Inhibitor

제품 번호
설명
Dutasteride, ≥98% (HPLC),
human
Dutasteride for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Dutasteride, United States Pharmacopeia (USP) Reference Standard,
human
Dutasteride, European Pharmacopoeia (EP) Reference Standard,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human SRD5A3,
human
MISSION® esiRNA, targeting mouse Srd5a3,
mouse