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Merck

SMAD4

SMAD family member 4

동의어:
DPC4, JIP, MADH4, MYHRS
:
UniProtKB ID:
Clone ID:
  • Human(4089) Summary: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009]
  • Mouse(17128) SMAD family member 4
  • Rat(50554) SMAD family member 4
  • dog(476196) SMAD family member 4
  • domestic cat(101093650) SMAD family member 4
  • Zebrafish(30640) MAD homolog 4 (Drosophila)
  • domestic guinea pig(100717853) SMAD family member 4
  • naked mole-rat(101703764) SMAD family member 4
  • sheep(443171) SMAD family member 4
  • cow(540248) SMAD family member 4
  • Horse(100033846) SMAD family member 4
  • Goat(100861019) SMAD family member 4

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ELISA

제품 번호
설명
Human Smad4 ELISA, for serum, plasma and cell culture supernatants,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-SMAD4 antibody produced in mouse, clone 4G1C6, ascites fluid,
종별 반응성
human
응용분야
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-SMAD4 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9774, purified immunoglobulin, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-SMAD4 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat, sheep
응용분야
immunohistochemistry
western blot
ANTI-SMAD4 antibody produced in mouse, clone 3D7, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
proximity ligation assay

western blot
ANTI-SMAD4 antibody produced in mouse, clone 2G4, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot

Proteins

제품 번호
설명
SMAD4, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human SMAD4,
human
MISSION® esiRNA, targeting mouse Smad4,
mouse