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Merck

SLC6A4

solute carrier family 6 (neurotransmitter transporter), member 4

동의어:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
:
UniProtKB ID:
Clone ID:
  • Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
  • Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
  • domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

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Small Molecule - Antagonist

제품 번호
설명
Diphenyl-4-pyridylmethane, 99%,
rat
N-Ethylmaleimide, purum p.a., ≥99.0% (HPLC),
human
N-Ethylmaleimide, BioUltra, ≥99.0% (HPLC),
human
4-Benzylpyridine, 98%,
rat
N-Ethylmaleimide, BioXtra, ≥98% (HPLC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-SLC6A4 antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
Anti-SLC6A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-SLC6A4 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
bovine, human, mouse, rat
응용분야
ELISA
flow cytometry

immunofluorescence
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
종별 반응성
mouse, rat
응용분야
Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
western blot

Small Molecule - Inhibitor

제품 번호
설명
Dapoxetine hydrochloride, ≥98% (HPLC),
human
Sertraline for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Sertraline for peak identification, European Pharmacopoeia (EP) Reference Standard,
human
Sertraline hydrochloride, United States Pharmacopeia (USP) Reference Standard,
human
Sertraline hydrochloride, European Pharmacopoeia (EP) Reference Standard,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human SLC6A4,
human