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Merck

SHANK2

SH3 and multiple ankyrin repeat domains 2

동의어:
AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
:
UniProtKB ID:
Clone ID:
  • Human(22941) Summary: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(210274) SH3/ankyrin domain gene 2
  • Rat(171093) SH3 and multiple ankyrin repeat domains 2
  • sheep(101117805) SH3 and multiple ankyrin repeat domains 2
  • domestic cat(101088878) SH3 and multiple ankyrin repeat domains 2
  • Zebrafish(567595) SH3 and multiple ankyrin repeat domains 2
  • cow(618649) SH3 and multiple ankyrin repeat domains 2
  • Domestic Rabbit(100338286) SH3 and multiple ankyrin repeat domains 2
  • naked mole-rat(101704570) SH3 and multiple ankyrin repeat domains 2
  • chicken(428858) SH3 and multiple ankyrin repeat domains 2
  • domestic guinea pig(100732196) SH3 and multiple ankyrin repeat domains 2
  • dog(483677) SH3 and multiple ankyrin repeat domains 2

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-SHANK2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot
Anti-pan-Shank Antibody, clone N23B/49, clone N23B/49, from mouse,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-SHANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human SHANK2,
human
MISSION® esiRNA, targeting mouse Shank2,
mouse