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Merck

SFTPB

surfactant protein B

동의어:
PSP-B, SFTB3, SFTP3, SMDP1, SP-B
:
UniProtKB ID:
Clone ID:
  • Human(6439) Summary: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]
  • Mouse(20388) surfactant associated protein B
  • Rat(192155) surfactant protein B
  • naked mole-rat(101700017) surfactant protein B
  • domestic guinea pig(100379548) surfactant associated protein B
  • dog(100688334) surfactant protein B
  • Horse(100034028) surfactant protein B
  • domestic cat(101091359) surfactant protein B
  • sheep(443043) surfactant protein B
  • cow(507398) surfactant protein B

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-SFTPB antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, guinea pig, human, rat
응용분야
immunohistochemistry
western blot
Anti-SFTPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-SFTPB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-Surfactant Protein B Antibody, from rabbit, purified by affinity chromatography,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-SFTPB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human SFTPB,
human