์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck

SESN1

sestrin 1

๋™์˜์–ด:
PA26, SEST1
์ข…:
Human SESN1 (27244), Mouse Sesn1 (140742), Rat Sesn1 (294518), domestic cat SESN1 (101099380), cow SESN1 (538226), sheep SESN1 (101115970), dog SESN1 (481956), Zebrafish sesn1 (436933), naked mole-rat Sesn1 (101699483), chicken SESN1 (421766)
UniProtKB ID:
Q9Y6P5, Q2M2B7, Q5T316, Q9NV00, Q9UPD5, Q9Y6P6
Clone ID:
  • Human(27244) Summary: This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
  • Mouse(140742) sestrin 1
  • Rat(294518) sestrin 1
  • domestic cat(101099380) sestrin 1
  • cow(538226) sestrin 1
  • sheep(101115970) sestrin 1
  • dog(481956) sestrin 1
  • Zebrafish(436933) sestrin 1
  • naked mole-rat(101699483) sestrin 1
  • chicken(421766) sestrin 1
  • domestic guinea pig(100713452) sestrin 1

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Antibodies

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
์‘์šฉ๋ถ„์•ผ
SAB5701369
Anti-sestrin 1 antibody produced in rabbit, ,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human, mouse, rat
์‘์šฉ๋ถ„์•ผ
immunohistochemistry
western blot
SAB1401644
Anti-SESN1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
western blot
HPA073659
Anti-SESN1 antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
immunofluorescence
SAB2107096
Anti-SESN1 antibody produced in rabbit, affinity isolated antibody,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
์‘์šฉ๋ถ„์•ผ
western blot

Proteins

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
SRP0411
Sestrin 1 human, recombinant, expressed in baculovirus infected Sf9 cells, โ‰ฅ44% (SDS-PAGE),
์ข…
human

esiRNA

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
EHU139941
MISSIONยฎ esiRNA, targeting human SESN1,
์ข…
human
EMU178621
MISSIONยฎ esiRNA, targeting mouse Sesn1,
์ข…
mouse