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Merck

RGS14

regulator of G-protein signaling 14

동의어:
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UniProtKB ID:
Clone ID:
  • Human(10636) Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Mouse(51791) regulator of G-protein signaling 14
  • Rat(114705) regulator of G-protein signaling 14
  • dog(489092) regulator of G-protein signaling 14
  • sheep(101106525) regulator of G-protein signaling 14
  • domestic cat(101099431) regulator of G-protein signaling 14
  • cow(532605) regulator of G-protein signaling 14
  • domestic guinea pig(100728156) regulator of G-protein signaling 14
  • naked mole-rat(101722596) regulator of G-protein signaling 14
  • chicken(769193) regulator of G-protein signaling 14

Custom & Knockdown Gene Products

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-RGS14 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-RGS14 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-RGS14 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Rgs14,
mouse
MISSION® esiRNA, targeting human RGS14,
human