์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck

PTPRN

protein tyrosine phosphatase, receptor type, N

๋™์˜์–ด:
IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
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UniProtKB ID:
Clone ID:
  • Human(5798) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
  • Mouse(19275) protein tyrosine phosphatase, receptor type, N
  • Rat(116660) protein tyrosine phosphatase, receptor type, N
  • Domestic Rabbit(100355368) protein tyrosine phosphatase, receptor type, N
  • domestic cat(101100657) protein tyrosine phosphatase, receptor type, N
  • dog(478921) protein tyrosine phosphatase, receptor type, N
  • cow(286810) protein tyrosine phosphatase, receptor type, N
  • sheep(101113312) protein tyrosine phosphatase, receptor type, N
  • domestic guinea pig(100733759) protein tyrosine phosphatase, receptor type, N
  • naked mole-rat(101718650) protein tyrosine phosphatase, receptor type, N

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Antibodies

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Anti-PTPRN antibody produced in rabbit, affinity isolated antibody,
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dog, human, mouse, rabbit, rat
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western blot
Monoclonal Anti-PTPRN antibody produced in mouse, clone 8E3, purified immunoglobulin, buffered aqueous solution,
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human
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ELISA
western blot
Anti-PTPRN antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
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human
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immunohistochemistry
Anti-PTPRN antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody,
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human
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immunofluorescence
Anti-ICA 512/RESP18 Antibody, clone 1348-D29-1, ,
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human
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immunofluorescence
western blot

Proteins

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PTPIA2 Active human, recombinant, expressed in E. coli, โ‰ฅ90% (SDS-PAGE),
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human

esiRNA

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MISSIONยฎ esiRNA, targeting human PTPRN,
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human
MISSIONยฎ esiRNA, targeting mouse Ptprn,
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mouse