PTK2B
protein tyrosine kinase 2 beta
동의어:
CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK
종:
Human PTK2B (2185), Mouse Ptk2b (19229), Rat Ptk2b (50646), domestic cat PTK2B (101091691), dog PTK2B (486102), chicken PTK2B (421998), domestic guinea pig Ptk2b (100734027), naked mole-rat Ptk2b (101714384), cow PTK2B (541008), sheep PTK2B (101106906) ...더
UniProtKB ID:
Clone ID:
- Human(2185) Summary: This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19229) PTK2 protein tyrosine kinase 2 beta
- Rat(50646) protein tyrosine kinase 2 beta
- domestic cat(101091691) PTK2B protein tyrosine kinase 2 beta
- dog(486102) PTK2B protein tyrosine kinase 2 beta
- chicken(421998) PTK2B protein tyrosine kinase 2 beta
- domestic guinea pig(100734027) protein tyrosine kinase 2 beta
- naked mole-rat(101714384) protein tyrosine kinase 2 beta
- cow(541008) PTK2B protein tyrosine kinase 2 beta
- sheep(101106906) PTK2B protein tyrosine kinase 2 beta
- Domestic Rabbit(100342358) PTK2B protein tyrosine kinase 2 beta
- Horse(100054547) PTK2B protein tyrosine kinase 2 beta
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-phospho-Pyk2/CAKβ/FAK2 (Tyr402) Antibody, Upstate®, from rabbit,
종별 반응성
human, rat
응용분야
immunocytochemistry
western blot
western blot
Anti-Phospho-PTK2B-Y402 antibody produced in rabbit, ,
종별 반응성
human, mouse
응용분야
western blot
Anti-PYK2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
immunohistochemistry
Anti-PTK2B (Ab-402) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PYK2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot