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Merck

PRKCD

protein kinase C, delta

동의어:
MAY1, PKCD, nPKC-delta
:
UniProtKB ID:
Clone ID:
  • Human(5580) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18753) protein kinase C, delta
  • Rat(170538) protein kinase C, delta
  • domestic cat(101087716) protein kinase C, delta
  • chicken(415905) protein kinase C, delta
  • domestic guinea pig(100726624) protein kinase C, delta
  • naked mole-rat(101718422) protein kinase C, delta
  • sheep(101107639) protein kinase C, delta
  • Domestic Rabbit(100008966) protein kinase C, delta
  • cow(505708) protein kinase C, delta
  • sheep(100294651) protein kinase C, delta
  • dog(494005) protein kinase C, delta

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Small Molecule - Agonist

제품 번호
설명
Oleic acid, ≥99% (GC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PKC δ antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-phospho-PKC δ (pTyr52) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Protein Kinase Cδ antibody produced in rabbit, whole antiserum,
종별 반응성
rat
응용분야
dot blot
microarray

western blot
Anti-phospho-PKCδ (Ser664) Antibody, Upstate®, from rabbit,
종별 반응성
human
응용분야
western blot
Anti-PRKCD antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
Phorbol 12,13-dibutyrate, ≥98% (TLC), powder,
mouse
H-7 dihydrochloride, ≥98% (HPLC),
human
Tamoxifen citrate salt, ≥99%,
human
Oleic acid, ≥99% (GC),
human
UCN-01, ≥97% (HPLC), powder,
human

Proteins

제품 번호
설명
PKC-δ, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human
Protein Kinase Cδ isozyme human, >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Prkcd,
mouse
MISSION® esiRNA, targeting human PRKCD,
human