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Merck

PPARA

peroxisome proliferator-activated receptor alpha

동의어:
NR1C1, PPAR, PPARalpha, hPPAR
:
UniProtKB ID:
Clone ID:
  • Human(5465) Summary: Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
  • Mouse(19013) peroxisome proliferator activated receptor alpha
  • Rat(25747) peroxisome proliferator activated receptor alpha
  • domestic guinea pig(100135604) peroxisome proliferator activated receptor alpha
  • chicken(374120) peroxisome proliferator-activated receptor alpha
  • naked mole-rat(101725514) peroxisome proliferator-activated receptor alpha
  • Domestic Rabbit(100009308) peroxisome proliferator-activated receptor alpha
  • Goat(100861393) peroxisome proliferator-activated receptor alpha
  • sheep(100190976) peroxisome proliferator-activated receptor alpha
  • dog(403654) peroxisome proliferator-activated receptor alpha
  • Horse(100049840) peroxisome proliferator-activated receptor alpha
  • domestic cat(101095837) peroxisome proliferator-activated receptor alpha
  • domestic cat(100049013) peroxisome proliferator-activated receptor alpha
  • cow(281992) peroxisome proliferator-activated receptor alpha

Custom & Knockdown Gene Products

Small Molecule - Activator

제품 번호
설명
Fenofibrate, ≥99%, powder,
human
2-(p-Chlorophenoxy)-2-methylpropionic acid, 97%,
mouse, human
WY-14643, ,
rat, human, mouse
Bezafibrate, ≥98%, solid,
mouse, human

Small Molecule - Agonist

제품 번호
설명
Fenofibrate, ≥99%, powder,
human
Fenofibrate, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Fenofibrate Related Compound B, United States Pharmacopeia (USP) Reference Standard,
human
Fenofibric acid, analytical standard,
human
Fenofibrate, United States Pharmacopeia (USP) Reference Standard,
human

Small Molecule - Antagonist

제품 번호
설명
Troglitazone, ≥98% (HPLC),
human
GW0742, ≥98% (HPLC),
human
N-Oleoylethanolamine, ~98% (TLC),
human, mouse, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PPARA, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, goat, guinea pig, horse, human, rabbit
응용분야
western blot
Monoclonal Anti-PPARA antibody produced in mouse, clone 1A8, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence
Anti-PPARA antibody produced in rabbit, IgG fraction of antiserum,
종별 반응성
human
응용분야
western blot
Anti-PPARA antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, rat
응용분야
western blot
Anti-PPAR-α antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

western blot

Proteins

제품 번호
설명
PPARα isotype, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
human
PPARα, ligand binding domain (170-468) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
human
PPARα isotype, ligand binding domain, GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
human
PPAR, α human, recombinant, expressed in E. coli, ≥75% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PPARA,
human