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Merck

PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

동의어:
LH2, TLH
:
UniProtKB ID:
Clone ID:
  • Human(5352) Summary: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(26432) procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
  • Rat(300901) procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
  • dog(485702) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • domestic cat(101085741) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • naked mole-rat(101708679) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • domestic guinea pig(100735218) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • Zebrafish(100036767) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • sheep(101103613) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • chicken(424882) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • cow(533642) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
  • Horse(100061030) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PLOD2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, horse, human, mouse, pig, rabbit, rat
응용분야
immunohistochemistry
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PLOD2,
human
MISSION® esiRNA, targeting mouse Plod2,
mouse