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Merck

PLCG1

phospholipase C, gamma 1

동의어:
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
:
UniProtKB ID:
Clone ID:
  • Human(5335) Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18803) phospholipase C, gamma 1
  • Rat(25738) phospholipase C, gamma 1
  • naked mole-rat(101705192) phospholipase C, gamma 1
  • chicken(419175) phospholipase C, gamma 1
  • dog(485874) phospholipase C, gamma 1
  • Zebrafish(373867) phospholipase C, gamma 1
  • domestic cat(101092925) phospholipase C, gamma 1
  • cow(281987) phospholipase C, gamma 1
  • domestic guinea pig(100716986) phospholipase C, gamma 1
  • sheep(101103341) phospholipase C, gamma 1

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-PLCγ-1 Antibody, clone B-6-4, clone B-6-4, 1 mg/mL, Upstate®,
종별 반응성
bovine, human, mouse, rabbit, rat
응용분야
immunoprecipitation (IP)
western blot
Anti-phospho-PLCG1 (pTyr783) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot
Anti-phospho-PLCG1 (pTyr783) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-Phospho-PLCG1-S1248 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-PLCγ-1 Antibody, Upstate®, from mouse,
종별 반응성
bovine, human, mouse, rabbit, rat
응용분야
immunocytochemistry
immunoprecipitation (IP)

western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Plcg1,
mouse
MISSION® esiRNA, targeting human PLCG1,
human