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Merck

PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

동의어:
PLA2G4, cPLA2-alpha
:
UniProtKB ID:
Clone ID:
  • Human(5321) Summary: This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008]
  • Mouse(18783) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • Rat(24653) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • dog(480048) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • Horse(100033889) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • cow(525072) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • Zebrafish(559087) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • domestic guinea pig(100715719) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • domestic cat(101082033) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • chicken(396394) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • sheep(101111472) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • naked mole-rat(101704061) phospholipase A2, group IVA (cytosolic, calcium-dependent)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-C-PLA2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-cPLA2 Antibody, clone 2F4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human
응용분야
affinity binding assay
immunohistochemistry

western blot
Monoclonal Anti-PLA2G4A antibody produced in mouse, clone 10G5, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-phospho-c-PLA2 (pSer505) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PLA2G4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PLA2G4A,
human
MISSION® esiRNA, targeting mouse Pla2g4a,
mouse