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Merck

PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

동의어:
PFK-2/FBPase-2
:
UniProtKB ID:
Clone ID:
  • Human(5208) Summary: The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18640) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • Rat(24640) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • Horse(100051146) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • naked mole-rat(101722273) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • domestic guinea pig(100713857) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • chicken(419850) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • domestic cat(101089572) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • dog(480011) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • sheep(101119324) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • cow(287019) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Phospho-PFKFB2-S483 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-PFKFB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-PFKFB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PFKFB2,
human
MISSION® esiRNA, targeting mouse Pfkfb2,
mouse