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Merck

PCSK1

proprotein convertase subtilisin/kexin type 1

동의어:
BMIQ12, NEC1, PC1, PC3, SPC3
:
UniProtKB ID:
Clone ID:
  • Human(5122) Summary: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]
  • Mouse(18548) proprotein convertase subtilisin/kexin type 1
  • Rat(25204) proprotein convertase subtilisin/kexin type 1
  • domestic guinea pig(100732445) proprotein convertase subtilisin/kexin type 1
  • naked mole-rat(101704290) proprotein convertase subtilisin/kexin type 1
  • cow(281967) proprotein convertase subtilisin/kexin type 1
  • domestic cat(101082627) proprotein convertase subtilisin/kexin type 1
  • Zebrafish(100005716) proprotein convertase subtilisin/kexin type 1
  • chicken(769230) proprotein convertase subtilisin/kexin type 1
  • Horse(100064886) proprotein convertase subtilisin/kexin type 1
  • dog(479149) proprotein convertase subtilisin/kexin type 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-PCSK1, (C-terminal) antibody produced in mouse, clone 2G12, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-PCSK1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human
응용분야
immunohistochemistry
western blot
Anti-PCSK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-PCSK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human PCSK1,
human
MISSION® esiRNA, targeting mouse Pcsk1,
mouse