콘텐츠로 건너뛰기
Merck

NR1H4

nuclear receptor subfamily 1, group H, member 4

동의어:
BAR, FXR, HRR-1, HRR1, RIP14
:
UniProtKB ID:
Clone ID:
  • Human(9971) Summary: This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(20186) nuclear receptor subfamily 1, group H, member 4
  • Rat(60351) nuclear receptor subfamily 1, group H, member 4
  • domestic cat(101096997) nuclear receptor subfamily 1, group H, member 4
  • naked mole-rat(101714263) nuclear receptor subfamily 1, group H, member 4
  • cow(540528) nuclear receptor subfamily 1, group H, member 4
  • domestic guinea pig(100734377) nuclear receptor subfamily 1, group H, member 4
  • Zebrafish(436847) nuclear receptor subfamily 1, group H, member 4
  • Horse(100052821) nuclear receptor subfamily 1, group H, member 4
  • chicken(373902) nuclear receptor subfamily 1, group H, member 4
  • dog(612928) nuclear receptor subfamily 1, group H, member 4
  • sheep(101105401) nuclear receptor subfamily 1, group H, member 4
  • Domestic Rabbit(100009485) nuclear receptor subfamily 1, group H, member 4

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

제품 번호
설명
Ursodeoxycholic acid, European Pharmacopoeia (EP) Reference Standard,
human
Ursodeoxycholic acid, ≥99%,
human
Chenodeoxycholic acid, European Pharmacopoeia (EP) Reference Standard,
human
Ursodeoxycholic acid, British Pharmacopoeia (BP) Reference Standard,
human
Chenodeoxycholic acid, British Pharmacopoeia (BP) Reference Standard,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-NR1H4 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, dog, guinea pig, horse, human, mouse, rat
응용분야
immunohistochemistry
western blot
Monoclonal Anti-NR1H4, (C-terminal) antibody produced in mouse, clone 1B10, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence

western blot
Anti-Farnesoid X Receptor/HRR1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
canine, human
응용분야
ELISA
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human NR1H4,
human
MISSION® esiRNA, targeting mouse Nr1h4,
mouse