NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
동의어:
APAA, UCE
종:
Human NAGPA (51172), Mouse Nagpa (27426), Rat Nagpa (360476), sheep NAGPA (101104545), cow NAGPA (515935), domestic cat NAGPA (101091582), dog NAGPA (490019), chicken NAGPA (416395), naked mole-rat Nagpa (101704527), domestic guinea pig Nagpa (100723215)
UniProtKB ID:
Clone ID:
- Human(51172) Summary: Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the protein's C-terminus contains multiple signals for trafficking it between lysosomes, the plasma membrane, and trans-Golgi network. [provided by RefSeq, Jul 2008]
- Mouse(27426) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- Rat(360476) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- sheep(101104545) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- cow(515935) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- domestic cat(101091582) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- dog(490019) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- chicken(416395) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- naked mole-rat(101704527) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
- domestic guinea pig(100723215) N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-NAGPA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
esiRNA
제품 번호
설명
종