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Merck

MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

동의어:
CLG4, CLG4A, MMP-II, MONA, TBE-1
:
UniProtKB ID:
Clone ID:
  • Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17390) matrix metallopeptidase 2
  • Rat(81686) matrix metallopeptidase 2
  • naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Zebrafish(337179) matrix metalloproteinase 2
  • Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • fruit fly(35997) Matrix metalloproteinase 2

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ELISA

제품 번호
설명
Human MMP-2 ELISA Kit, for serum, plasma, cell culture supernatant,
human
Mouse MMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
mouse

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-MMP-2 (Ab-3) Mouse mAb (42-5D11), liquid, clone 42-5D11, Calbiochem®,
종별 반응성
bovine, human, mouse, rat
응용분야
Anti-MMP-2 Antibody, catalytic domain, Chemicon®, from rabbit,
종별 반응성
human, mouse, rat
응용분야
immunoprecipitation (IP)
western blot
Anti-MMP2, IgG fraction of antiserum,
종별 반응성
bovine, dog, guinea pig, horse, human, mouse, rat, sheep
응용분야
immunohistochemistry
western blot
Anti- MMP2 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-MMP-2 Antibody, pro and active form, clone VB3, clone VB3, Chemicon®, from mouse,
종별 반응성
human
응용분야
ELISA
immunofluorescence

western blot

Small Molecule - Inhibitor

제품 번호
설명
CP-471474, ≥98% (HPLC),
human, rat, mouse
Marimastat, ≥98% (HPLC),
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
human, rat, mouse
CP-101537, ≥98% (HPLC),
human, rat, mouse

Proteins

제품 번호
설명
MMP-2 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
human
Matrix Metalloproteinase-2 human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
human
Matrix Metalloproteinase-2 from mouse, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
mouse, rat

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Mmp2,
mouse
MISSION® esiRNA, targeting human MMP2,
human