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MBD3

methyl-CpG binding domain protein 3

동의어:
:
UniProtKB ID:
Clone ID:
  • Human(53615) Summary: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. [provided by RefSeq, Jul 2008]
  • Mouse(17192) methyl-CpG binding domain protein 3
  • Rat(362834) methyl-CpG binding domain protein 3
  • domestic cat(101098692) methyl-CpG binding domain protein 3
  • Thale Cress(828069) methyl-CpG-binding domain-containing protein 3
  • chicken(770153) methyl-CpG binding domain protein 3
  • dog(485080) methyl-CpG binding domain protein 3
  • sheep(101119469) methyl-CpG binding domain protein 3
  • naked mole-rat(101696358) methyl-CpG binding domain protein 3
  • cow(616090) methyl-CpG binding domain protein 3
  • domestic guinea pig(100713224) methyl-CpG binding domain protein 3

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-MBD3 antibody produced in rabbit, ,
종별 반응성
mouse, rat
응용분야
immunohistochemistry
western blot
Anti-MBD3 Antibody, clone 1K19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, monkey, mouse, rat
응용분야
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human MBD3,
human
MISSION® esiRNA, targeting mouse Mbd3,
mouse