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Merck

MAPK9

mitogen-activated protein kinase 9

동의어:
JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK
:
UniProtKB ID:
Clone ID:
  • Human(5601) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
  • Mouse(26420) mitogen-activated protein kinase 9
  • Rat(50658) mitogen-activated protein kinase 9
  • Zebrafish(100149273) mitogen-activated protein kinase 9
  • chicken(395983) mitogen-activated protein kinase 9
  • cow(534125) mitogen-activated protein kinase 9
  • domestic cat(101084765) mitogen-activated protein kinase 9
  • Horse(100057961) mitogen-activated protein kinase 9
  • dog(474652) mitogen-activated protein kinase 9
  • Domestic Rabbit(100342664) mitogen-activated protein kinase 9
  • sheep(101120826) mitogen-activated protein kinase 9
  • domestic guinea pig(100714249) mitogen-activated protein kinase 9
  • naked mole-rat(101698286) mitogen-activated protein kinase 9

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Antibodies

제품 번호
설명
종별 반응성
응용분야
ANTI-MAPK9 antibody produced in mouse, clone 3C12, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
immunofluorescence

western blot
Anti-MAPK9 antibody produced in rabbit, ,
종별 반응성
human, mouse
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-Mapk9 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
Anti-phospho-MAPK9 (pThr183) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-SAPK antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
SP600125, ≥98% (HPLC),
human
Adenine, ≥99%,
human, rat, mouse
Adenine, BioReagent, suitable for cell culture,
human, rat, mouse
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
human, rat, mouse
α-Sexithiophene, ,
human, rat

Proteins

제품 번호
설명
JNK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Mapk9,
mouse
MISSION® esiRNA, targeting human MAPK9,
human