콘텐츠로 건너뛰기
Merck

MAPK1

mitogen-activated protein kinase 1

동의어:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
종:
UniProtKB ID:
Clone ID:
  • Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26413) mitogen-activated protein kinase 1
  • Rat(116590) mitogen activated protein kinase 1
  • chicken(373953) mitogen-activated protein kinase 1
  • Zebrafish(360144) mitogen-activated protein kinase 1
  • dog(477575) mitogen-activated protein kinase 1
  • domestic cat(101087614) mitogen-activated protein kinase 1
  • sheep(101115485) mitogen-activated protein kinase 1
  • cow(327672) mitogen-activated protein kinase 1
  • naked mole-rat(101706099) mitogen-activated protein kinase 1
  • domestic guinea pig(100715180) mitogen-activated protein kinase 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

제품 번호
설명
Phosphotyrosine MAPK1 / MAPK3 ELISA Kit, ,
human
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
rat, human, mouse

Antibodies

제품 번호
설명
종별 반응성
응용분야
[KO Validated]Anti-Erk2 antibody produced in mouse, [Knockout Validated]purified monoclonal antibody, buffered aqueous solution,
종별 반응성
human, mouse
응용분야
western blot
Anti-MAPK1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
응용분야
immunohistochemistry
western blot
Anti-MAPK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-MAPK1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-ERK2/MAPK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
xenopus, bovine, chicken, chimpanzee, human, mouse
응용분야
ELISA
western blot

Small Molecule - Inhibitor

제품 번호
설명
Adenine, BioReagent, suitable for plant cell culture, ≥99%,
human, rat, mouse
Adenine, ≥99%,
human, rat, mouse
Adenine, BioReagent, suitable for cell culture,
human, rat, mouse

Proteins

제품 번호
설명
ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human MAPK1,
human