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Merck

MAP3K12

mitogen-activated protein kinase kinase kinase 12

동의어:
DLK, MEKK12, MUK, ZPK, ZPKP1
:
UniProtKB ID:
Clone ID:
  • Human(7786) Summary: This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010]
  • Mouse(26404) mitogen-activated protein kinase kinase kinase 12
  • Rat(25579) mitogen activated protein kinase kinase kinase 12
  • naked mole-rat(101702332) mitogen-activated protein kinase kinase kinase 12
  • chicken(101669120) mitogen-activated protein kinase kinase kinase 12
  • Horse(100064002) mitogen-activated protein kinase kinase kinase 12
  • Zebrafish(404626) mitogen-activated protein kinase kinase kinase 12
  • chicken(101750914) mitogen-activated protein kinase kinase kinase 12
  • domestic cat(101087164) mitogen-activated protein kinase kinase kinase 12
  • cow(505427) mitogen-activated protein kinase kinase kinase 12
  • sheep(101102889) mitogen-activated protein kinase kinase kinase 12
  • Domestic Rabbit(100358158) mitogen-activated protein kinase kinase kinase 12
  • dog(607170) mitogen-activated protein kinase kinase kinase 12
  • domestic guinea pig(100731317) mitogen-activated protein kinase kinase kinase 12

Custom & Knockdown Gene Products

Antibodies

제품 번호
설명
종별 반응성
응용분야
ANTI-MAP3K12 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-MAP3K12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-MAP3K12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence

Proteins

제품 번호
설명
DLK, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human MAP3K12,
human
MISSION® esiRNA, targeting mouse Map3k12,
mouse