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Merck

LITAF

lipopolysaccharide-induced TNF factor

동의어:
PIG7, SIMPLE, TP53I7
:
UniProtKB ID:
Clone ID:
  • Human(9516) Summary: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2008]
  • Mouse(56722) LPS-induced TN factor
  • Rat(65161) lipopolysaccharide-induced TNF factor
  • chicken(374125) lipopolysaccharide-induced TNF factor
  • Zebrafish(431731) lipopolysaccharide-induced TNF factor
  • dog(490004) lipopolysaccharide-induced TNF factor
  • domestic cat(101083562) lipopolysaccharide-induced TNF factor
  • cow(520564) lipopolysaccharide-induced TNF factor
  • sheep(101109408) lipopolysaccharide-induced TNF factor
  • domestic guinea pig(100729493) lipopolysaccharide-induced TNF factor
  • naked mole-rat(101725320) lipopolysaccharide-induced TNF factor
  • Horse(100033923) lipopolysaccharide-induced TNF factor

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Small Molecule - Antagonist

제품 번호
설명
(+)-Thalidomide, ≥98% (HPLC), powder,
human, mouse, rat
(−)-Thalidomide, >98%, solid,
human, mouse, rat
Pentoxifylline, solid,
human, rat
4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one, solid,
human, rat
(±)-Thalidomide, ≥98%, powder,
human, mouse, rat

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-LITAF antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-LITAF antibody produced in mouse, clone 2E12, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
Anti-LITAF antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot
Anti-LITAF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-LITAF antibody produced in rabbit, ,
종별 반응성
human, mouse
응용분야
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

제품 번호
설명
(+)-Thalidomide, ≥98% (HPLC), powder,
human, mouse, rat
(−)-Thalidomide, >98%, solid,
human, mouse, rat
Pentoxifylline, solid,
human, rat
4-(3-Butoxy-4-methoxybenzyl)imidazolidin-2-one, solid,
human, rat
(±)-Thalidomide, ≥98%, powder,
human, mouse, rat

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Litaf,
mouse
MISSION® esiRNA, targeting mouse Litaf,
mouse
MISSION® esiRNA, targeting human LITAF,
human