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Merck

KDM2A

lysine (K)-specific demethylase 2A

동의어:
CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
:
UniProtKB ID:
Clone ID:
  • Human(22992) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
  • Mouse(225876) lysine (K)-specific demethylase 2A
  • Rat(361700) lysine (K)-specific demethylase 2A
  • Zebrafish(799441) lysine (K)-specific demethylase 2A
  • dog(483702) lysine (K)-specific demethylase 2A
  • chicken(425999) lysine (K)-specific demethylase 2A
  • cow(540141) lysine (K)-specific demethylase 2A
  • Horse(100052955) lysine (K)-specific demethylase 2A
  • domestic cat(101090549) lysine (K)-specific demethylase 2A
  • sheep(101108003) lysine (K)-specific demethylase 2A
  • naked mole-rat(101713712) lysine (K)-specific demethylase 2A
  • domestic guinea pig(100732285) lysine (K)-specific demethylase 2A

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-KDM2A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
bovine, canine, human, mouse, pig, rat
응용분야
ELISA
western blot

Proteins

제품 번호
설명
FBXL11 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥15% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Kdm2a,
mouse
MISSION® esiRNA, targeting human KDM2A,
human