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Merck

KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

동의어:
ERD2L3
:
UniProtKB ID:
Clone ID:
  • Human(11015) Summary: This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  • Mouse(105785) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • Rat(315131) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • chicken(418026) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • naked mole-rat(101706113) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • Zebrafish(393613) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • domestic guinea pig(100727776) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • domestic cat(101080390) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • cow(509687) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
  • dog(474509) KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-KDELR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-KDELR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human KDELR3,
human
MISSION® esiRNA, targeting mouse Kdelr3,
mouse