콘텐츠로 건너뛰기
Merck

KCNA3

potassium voltage-gated channel, shaker-related subfamily, member 3

동의어:
HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3
:
UniProtKB ID:
Clone ID:
  • Human(3738) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]
  • Mouse(16491) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Rat(29731) potassium voltage-gated channel, shaker-related subfamily, member 3
  • cow(525507) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic cat(101092201) potassium voltage-gated channel, shaker-related subfamily, member 3
  • dog(490110) potassium voltage-gated channel, shaker-related subfamily, member 3
  • chicken(404303) potassium voltage-gated channel, shaker-related subfamily, member 3
  • naked mole-rat(101719045) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic guinea pig(100721847) potassium voltage-gated channel, shaker-related subfamily, member 3
  • sheep(101105466) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Domestic Rabbit(100328945) potassium voltage-gated channel, shaker-related subfamily, member 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-KCNA3 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-KCNA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-KV1.3 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry
Anti-phospho-Kv1.3/KCNA3 (pTyr135) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Potassium Channel Kv1.3 Antibody, extracellular domain, Chemicon®, from rabbit,
종별 반응성
human, rat
응용분야
flow cytometry
western blot

Small Molecule - Blocker

제품 번호
설명
Charybdotoxin, ≥90% (HPLC),
mouse, rat, human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
human
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
human
Guanidine hydrochloride, ,
human
Guanidine hydrochloride, BioUltra, for molecular biology, ≥99.5% (AT),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human KCNA3,
human