JAK1
Janus kinase 1
동의어:
JAK1A, JAK1B, JTK3
종:
Human JAK1 (3716), Mouse Jak1 (16451), Rat Jak1 (84598), naked mole-rat Jak1 (101710283), domestic guinea pig Jak1 (100726895), Domestic Rabbit JAK1 (100352594), sheep JAK1 (101110716), domestic cat JAK1 (101084377), Horse JAK1 (100054008), cow JAK1 (537201) ...더
UniProtKB ID:
Clone ID:
- Human(3716) Summary: Janus kinase 1 (JAK1), is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon receptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and of a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs. [provided by RefSeq, Jul 2008]
- Mouse(16451) Janus kinase 1
- Rat(84598) Janus kinase 1
- naked mole-rat(101710283) Janus kinase 1
- domestic guinea pig(100726895) Janus kinase 1
- Domestic Rabbit(100352594) Janus kinase 1
- sheep(101110716) Janus kinase 1
- domestic cat(101084377) Janus kinase 1
- Horse(100054008) Janus kinase 1
- cow(537201) Janus kinase 1
- dog(442952) Janus kinase 1
- Zebrafish(30280) Janus kinase 1
- chicken(395681) Janus kinase 1
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ELISA
제품 번호
설명
종
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-Phospho-Jak1-Y1022/1023 antibody produced in rabbit, ,
종별 반응성
human, mouse
응용분야
immunofluorescence
western blot
western blot
Anti-phospho-JAK1 (pTyr1022) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-JAK1 (pTyr1022) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
western blot
Anti-JAK1 Antibody, clone 7Q1B2, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
immunohistochemistry
western blot
western blot
Anti-JAK1 Antibody, clone 1I13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
bovine, canine, human, monkey, mouse, porcine, rat
응용분야
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Proteins
제품 번호
설명
종
Jak1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
종
human
JAK1 Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human JAK1, amino acids 866-end, expressed by baculovirus in Sf21 insect cells. Activated in vitro by auto-phosphorylation. For use in Kinase Assays.,
종
human