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Merck

ITGAV

integrin, alpha V

동의어:
CD51, MSK8, VNRA, VTNR
:
UniProtKB ID:
Clone ID:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

Custom & Knockdown Gene Products

Small Molecule - Antagonist

제품 번호
설명
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Integrin αVβ3 Antibody, clone LM609, Alexa Fluor 555 Conjugate, clone LM609, from mouse, ALEXA FLUOR 555,
종별 반응성
avian, bovine, canine, chicken, human, monkey, pig, rabbit
응용분야
immunocytochemistry
Anti-Integrin αVβ5 Antibody, clone P1F6, azide free, clone P1F6, Chemicon®, from mouse,
종별 반응성
chicken, human
응용분야
flow cytometry
immunohistochemistry
Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6), liquid, clone 272-17E6, Calbiochem®,
종별 반응성
human
응용분야
Anti-Integrin αVβ3 Antibody, clone LM609, Azide Free, clone LM609, Chemicon®, from mouse,
종별 반응성
avian, bovine, canine, chicken, human, monkey, pig, rabbit
응용분야
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-Integrin αVβ3 Antibody, clone 27.1 (VNR-1), clone 27.1 (VNR-1), Chemicon®, from mouse,
종별 반응성
human
응용분야
immunofluorescence
immunoprecipitation (IP)

Proteins

제품 번호
설명
Human Integrin αVβ3 Protein, Triton X-100 Formulation, ,
human
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Itgav,
mouse
MISSION® esiRNA, targeting human ITGAV,
human