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Merck

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

동의어:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
:
UniProtKB ID:
Clone ID:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

제품 번호
설명
Metoclopramide, VETRANAL®, analytical standard,
human
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
human
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
human
SR 57227A, solid,
human
Metoclopramide hydrochloride, solid,
human

Small Molecule - Allosteric Modulator

제품 번호
설명
DCEBIO, ≥98% (HPLC), solid,
human

Small Molecule - Antagonist

제품 번호
설명
Ondansetron Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Ondansetron hydrochloride, United States Pharmacopeia (USP) Reference Standard,
human
Alosetron hydrochloride, ≥98% (HPLC),
human
Ondansetron for LC system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Ondansetron for TLC system suitability, European Pharmacopoeia (EP) Reference Standard,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Serotonin receptor 3A/HTR3A, from rabbit, purified by affinity chromatography,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry

Small Molecule - Blocker

제품 번호
설명
Trimipramine maleate salt, ≥98% (TLC), powder,
human
Zimelidine dihydrochloride, solid,
human

Small Molecule - Inhibitor

제품 번호
설명
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
human
Fluvoxamine maleate, solid,
human
Sertraline hydrochloride, ≥98% (HPLC),
human
Citalopram hydrobromide, ≥98% (HPLC),
human

Small Molecule - Ligand

제품 번호
설명
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
human

Small Molecule - Metabolite

제품 번호
설명
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
human

Small Molecule - Precursor

제품 번호
설명
5-Hydroxy-L-tryptophan, powder,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Htr3a,
mouse
MISSION® esiRNA, targeting human HTR3A,
human