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Merck

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

동의어:
5-HT(2B), 5-HT2B
:
UniProtKB ID:
Clone ID:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

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Small Molecule - Agonist

제품 번호
설명
BW 723C86, ≥98% (HPLC),
human
Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,
human
Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,
human
α-Methylserotonin maleate salt, ≥98% (HPLC),
human

Small Molecule - Allosteric Modulator

제품 번호
설명
DCEBIO, ≥98% (HPLC), solid,
human

Small Molecule - Antagonist

제품 번호
설명
Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,
human
Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,
human
Cyclobenzaprine hydrochloride, ,
human
Ketanserin (+)-tartrate salt, ≥97%, solid,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-HTR2B (N-terminal) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
bovine, canine, guinea pig, horse, human, mouse, pig
응용분야
western blot
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunofluorescence

western blot
Monoclonal Anti-Htr2B Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14576, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
western blot

Small Molecule - Blocker

제품 번호
설명
Trimipramine maleate salt, ≥98% (TLC), powder,
human
Zimelidine dihydrochloride, solid,
human

Small Molecule - Inhibitor

제품 번호
설명
Nortriptyline hydrochloride, ≥98% (HPLC), powder,
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
human
Fluvoxamine maleate, solid,
human
Sertraline hydrochloride, ≥98% (HPLC),
human

Small Molecule - Ligand

제품 번호
설명
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
human

Small Molecule - Metabolite

제품 번호
설명
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
human

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
Mifepristone, ≥98%,
human, mouse, rat
Clozapine, ,
human, rat

Small Molecule - Precursor

제품 번호
설명
5-Hydroxy-L-tryptophan, powder,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human HTR2B,
human