콘텐츠로 건너뛰기
Merck

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

동의어:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
종:
Human HTR1B (3351), Mouse Htr1b (15551), Rat Htr1b (25075), chicken HTR1B (421858), Zebrafish htr1b (561647), dog HTR1B (403741), cow HTR1B (317707), Horse HTR1B (100009680), domestic cat HTR1B (100144391), Domestic Rabbit HTR1B (100009594) ...더
UniProtKB ID:
P28222, Q4VAY7
Clone ID:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

제품 번호
설명
종
N1415
Naratriptan hydrochloride, ≥98% (HPLC),
종
human
1457469
Naratriptan hydrochloride, United States Pharmacopeia (USP) Reference Standard,
종
human
Y0000027
Sumatriptan for system suitability, European Pharmacopoeia (EP) Reference Standard,
종
human
S1198
Sumatriptan succinate, ≥98% (HPLC), solid,
종
human
SML0248
Zolmitriptan, ≥98% (HPLC),
종
human

Small Molecule - Allosteric Modulator

제품 번호
설명
종
D9190
DCEBIO, ≥98% (HPLC), solid,
종
human

Small Molecule - Antagonist

제품 번호
설명
종
G5793
GR 127935 hydrochloride hydrate, >98% (HPLC), powder,
종
human
M149
Methiothepin mesylate salt, ≥98% (HPLC), solid,
종
human
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
종
human
T6154
Trazodone hydrochloride, ≥99% (HPLC), powder,
종
human
M137
Methysergide maleate salt, solid,
종
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
SAB4501470
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence
immunohistochemistry
SAB4501471
Anti-HTR1B antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence
western blot
SAB2500924
Anti-Serotonin Receptor 1B/HTR1B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
canine, human, mouse, rat
응용분야
ELISA
western blot

Small Molecule - Blocker

제품 번호
설명
종
P8688
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
종
human
T6154
Trazodone hydrochloride, ≥99% (HPLC), powder,
종
human
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
종
human
Z101
Zimelidine dihydrochloride, solid,
종
human

Small Molecule - Inhibitor

제품 번호
설명
종
T6154
Trazodone hydrochloride, ≥99% (HPLC), powder,
종
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
종
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
종
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
종
human
F2802
Fluvoxamine maleate, solid,
종
human

Small Molecule - Ligand

제품 번호
설명
종
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
종
human

Small Molecule - Metabolite

제품 번호
설명
종
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
종
human

Small Molecule - Precursor

제품 번호
설명
종
H9772
5-Hydroxy-L-tryptophan, powder,
종
human

esiRNA

제품 번호
설명
종
EMU044151
MISSION® esiRNA, targeting mouse Htr1b,
종
mouse