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Merck

HTR1A

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

동의어:
5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
:
UniProtKB ID:
Clone ID:
  • Human(3350) Summary: This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]
  • Mouse(15550) 5-hydroxytryptamine (serotonin) receptor 1A
  • Rat(24473) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • chicken(431581) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • naked mole-rat(101718872) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • dog(487230) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic guinea pig(100301563) 5-hydroxytryptamine (serotonin) receptor 1A
  • cow(407137) 5-hydroxytryptamine (serotonin) receptor 1A
  • Horse(100009683) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • domestic cat(101101542) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • Domestic Rabbit(100008780) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
  • sheep(101105852) 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

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Small Molecule - Agonist

제품 번호
설명
Buspirone hydrochloride, ,
human
(R)-(+)-8-Hydroxy-DPAT hydrobromide, ≥98% (HPLC), solid,
human
Buspirone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
human
Buspirone for system suitability, European Pharmacopoeia (EP) Reference Standard,
human
Buspirone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
human

Small Molecule - Allosteric Modulator

제품 번호
설명
DCEBIO, ≥98% (HPLC), solid,
human

Small Molecule - Antagonist

제품 번호
설명
WAY-100635 maleate salt, powder,
human
GR 103691, ≥98% (HPLC), solid,
rat
BMY 7378 dihydrochloride, ≥98% (HPLC), solid,
human
Alverine citrate salt, ,
human
Alverine citrate, British Pharmacopoeia (BP) Reference Standard,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-5-HT-1A antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
Anti-5HT1A antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot
Anti-HTR1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-Serotonin antibody produced in rabbit, whole antiserum,
종별 반응성
human, rat
응용분야
immunohistochemistry
Anti-Htr1a antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot

Small Molecule - Blocker

제품 번호
설명
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
human
Trazodone hydrochloride, ≥99% (HPLC), powder,
human
Trimipramine maleate salt, ≥98% (TLC), powder,
human
Zimelidine dihydrochloride, solid,
human

Small Molecule - Inhibitor

제품 번호
설명
Vilazodone hydrochloride, ≥98% (HPLC),
human
Vilazodone hydrochloride solution, 1 mg/mL (Methanol:DMSO (90:10) (v/v)), certified reference material, ampule of 1 mL, Cerilliant®,
human
1,2,3,4-Tetrahydroisoquinoline, 95%,
rat, human
Trazodone hydrochloride, ≥99% (HPLC), powder,
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
human

Small Molecule - Ligand

제품 번호
설명
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
human

Small Molecule - Metabolite

제품 번호
설명
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
human

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
BP897, >98% (HPLC), solid,
human, rat
Mifepristone, ≥98%,
human, mouse, rat
Haloperidol, powder,
human, rat
Clozapine, ,
human, rat

Small Molecule - Precursor

제품 번호
설명
5-Hydroxy-L-tryptophan, powder,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human HTR1A,
human