HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
동의어:
HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
종:
Human HIF1A (3091), Mouse Hif1a (15251), Rat Hif1a (29560), dog HIF1A (480348), domestic guinea pig Hif1a (100713113), naked mole-rat Hif1a (101715845), Domestic Rabbit HIF1A (100009579), sheep HIF1A (443519), cow HIF1A (281814), domestic cat HIF1A (101083686)
UniProtKB ID:
Clone ID:
- Human(3091) Summary: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
- Mouse(15251) hypoxia inducible factor 1, alpha subunit
- Rat(29560) hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- dog(480348) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- domestic guinea pig(100713113) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- naked mole-rat(101715845) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- Domestic Rabbit(100009579) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- sheep(443519) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- cow(281814) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- domestic cat(101083686) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- chicken(374177) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
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ELISA
제품 번호
설명
종
Human HIF-1 alpha ELISA Kit, for cell culture supernatants, plasma, and serum samples,
종
human
Antibodies
제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-HIF-1α antibody produced in mouse, ~1 mg/mL, clone OZ12, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
immunoprecipitation (IP)
immunoprecipitation (IP)
Monoclonal Anti-HIF-1 α antibody produced in mouse, clone ESEE122, 1 mg/mL, purified immunoglobulin,
종별 반응성
bovine, human, mouse, rat
응용분야
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
Anti-Hypoxia Inducible Factor 1 α Antibody, clone H1α67, clone H1alpha67, Chemicon®, from mouse,
종별 반응성
ferret, human, mouse, rat
응용분야
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HIF-1α Antibody, from rabbit, purified by affinity chromatography,
종별 반응성
human
응용분야
western blot
Monoclonal Anti-HIF1A, (C-terminal) antibody produced in mouse, clone 1D4, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Proteins
제품 번호
설명
종
HIF-1 α N-terminal activation domain (530-698) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
종
human