์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
MilliporeSigma

HDAC5

histone deacetylase 5

๋™์˜์–ด:
HD5, NY-CO-9
์ข…:
UniProtKB ID:
Clone ID:
  • Human(10014) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(15184) histone deacetylase 5
  • Rat(84580) histone deacetylase 5
  • domestic guinea pig(100722799) histone deacetylase 5
  • domestic cat(101098019) histone deacetylase 5
  • naked mole-rat(101721186) histone deacetylase 5
  • cow(504242) histone deacetylase 5
  • sheep(101113686) histone deacetylase 5
  • dog(490941) histone deacetylase 5

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
์‘์šฉ๋ถ„์•ผ
Anti-HDAC5 (Ab-498) antibody produced in rabbit, affinity isolated antibody,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human, mouse, rat
์‘์šฉ๋ถ„์•ผ
immunohistochemistry
western blot
Anti-HDAC5 antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
immunofluorescence
immunohistochemistry
Anti-phospho-HDAC5 (pSer259) antibody produced in rabbit, affinity isolated antibody,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human, mouse, rat
์‘์šฉ๋ถ„์•ผ
ELISA
western blot
Anti-Hdac5 Antibody Produced In Rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human
์‘์šฉ๋ถ„์•ผ
immunohistochemistry
Anti-Phospho-HDAC5-S498 antibody produced in rabbit, ,
์ข…๋ณ„ ๋ฐ˜์‘์„ฑ
human, mouse, rat
์‘์šฉ๋ถ„์•ผ
immunohistochemistry
western blot

Small Molecule - Inhibitor

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
CIโˆ’994, โ‰ฅ98% (HPLC), powder,
์ข…
human
Romidepsin, โ‰ฅ98% (HPLC),
์ข…
human

Proteins

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
HDAC-5 human, recombinant, expressed in baculovirus infected insect cells, โ‰ฅ80% (SDS-PAGE),
์ข…
human

esiRNA

์ œํ’ˆ ๋ฒˆํ˜ธ
์„ค๋ช…
์ข…
MISSIONยฎ esiRNA, targeting human HDAC5,
์ข…
human
MISSIONยฎ esiRNA, targeting mouse Hdac5,
์ข…
mouse