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Merck

GRN

granulin

동의어:
CLN11, GEP, GP88, PCDGF, PEPI, PGRN
종:
UniProtKB ID:
Clone ID:
  • Human(2896) Summary: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
  • Mouse(14824) granulin
  • Rat(29143) granulin
  • fruit fly(40962) grain
  • dog(480501) granulin
  • Horse(100051035) granulin
  • domestic cat(101100680) granulin
  • cow(767942) granulin
  • sheep(101115470) granulin
  • Domestic Rabbit(100349528) granulin
  • domestic guinea pig(100135533) granulin
  • naked mole-rat(101715753) granulin

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ELISA

제품 번호
설명
Mouse Grn / Granulins ELISA Kit, ,
mouse
Human PGRN ELISA Kit, for cell culture supernatants, plasma, and serum samples,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-GRN, (C-terminal) antibody produced in mouse, clone 1A8, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
Anti-GRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-GRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
immunohistochemistry
Anti-GRN antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-Granulin (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
western blot

Proteins

제품 번호
설명
Progranulin rat, recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE),
rat
Progranulin human, recombinant, expressed in HEK 293 cells, untagged, >95% (SDS-PAGE),
human
Granulin C human, recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Grn,
mouse
MISSION® esiRNA, targeting human GRN,
human