콘텐츠로 건너뛰기
Merck

GRIN1

glutamate receptor, ionotropic, N-methyl D-aspartate 1

동의어:
GluN1, MRD8, NMDA1, NMDAR1, NR1
종:
Human GRIN1 (2902), Mouse Grin1 (14810), Rat Grin1 (24408), naked mole-rat Grin1 (101720185), Horse GRIN1 (100059861), chicken GRIN1 (404296), sheep GRIN1 (443281), cow GRIN1 (100336579), domestic guinea pig Grin1 (100301989), dog GRIN1 (494007)
UniProtKB ID:
Q05586, A6NLK7, A6NLR1, C9K0X1, P35437, Q12867, Q12868, Q5VSF3
Clone ID:
  • Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  • Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
  • domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

제품 번호
설명
종
S4250
D-Serine, ≥98% (TLC),
종
human
S2876
Spermine tetrahydrochloride, powder or crystals,
종
human
T0625
Taurine, ≥99%,
종
human, rat
C3909
D-Cycloserine, synthetic,
종
human
M3262
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
종
human, rat

Small Molecule - Allosteric Modulator

제품 번호
설명
종
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
종
human
1000554
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
종
human
BP1172
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
종
human

Small Molecule - Antagonist

제품 번호
설명
종
M216
MDL 105,519, ≥98% (HPLC), solid,
종
rat, human
SML0053
CP-101,606, ≥98% (HPLC),
종
human
I2892
Ifenprodil (+)-tartrate salt, ,
종
human
A0384
Arcaine sulfate salt, ,
종
human
C104
(±)-CPP, solid,
종
rat, human

Antibodies

제품 번호
설명
종별 반응성
응용분야
SAB4501301
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4500261
Anti-GPRIN1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot
SAB4501302
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
western blot
SAB4501303
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunohistochemistry
western blot
SAB2500698
Anti-NMDA Receptor 1/GRIN1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse
응용분야
ELISA
immunofluorescence

Small Molecule - Blocker

제품 번호
설명
종
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
종
human
A7127
Agmatine sulfate salt, ≥97%, powder,
종
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
종
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
종
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
종
human

Small Molecule - Inhibitor

제품 번호
설명
종
T0625
Taurine, ≥99%,
종
human, rat
P0547
Pentamidine isethionate salt, powder,
종
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
종
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
종
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
종
human

esiRNA

제품 번호
설명
종
EHU157091
MISSION® esiRNA, targeting human GRIN1,
종
human
EMU049051
MISSION® esiRNA, targeting mouse Grin1,
종
mouse