콘텐츠로 건너뛰기
Merck

FGFR2

fibroblast growth factor receptor 2

동의어:
BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
:
UniProtKB ID:
Clone ID:
  • Human(2263) Summary: The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
  • Mouse(14183) fibroblast growth factor receptor 2
  • Rat(25022) fibroblast growth factor receptor 2
  • dog(415125) fibroblast growth factor receptor 2
  • domestic cat(101095198) fibroblast growth factor receptor 2
  • chicken(396259) fibroblast growth factor receptor 2
  • Zebrafish(352940) fibroblast growth factor receptor 2
  • naked mole-rat(101709077) fibroblast growth factor receptor 2
  • Domestic Rabbit(100009417) fibroblast growth factor receptor 2
  • Horse(100033956) fibroblast growth factor receptor 2
  • cow(404193) fibroblast growth factor receptor 2
  • domestic guinea pig(100379152) fibroblast growth factor receptor 2
  • sheep(443548) fibroblast growth factor receptor 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

제품 번호
설명
Phosphotyrosine FGFR2 / Fibroblast Growth Factor Receptor 2 ELISA Kit, ,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Fibroblast Growth Factor Receptor-2, Cytoplasmic antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-FGFR2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
ELISA
immunohistochemistry

western blot
Anti-FGFR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-Fibroblast Growth Factor Receptor-2, Extracellular antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
[KO Validated]Anti-FGFR2 Antibody, clone 0O6A9, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
western blot

Proteins

제품 번호
설명
FGFR2 (285-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human FGFR2,
human