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Merck

EDN3

endothelin 3

동의어:
ET-3, ET3, HSCR4, PPET3, WS4B
:
UniProtKB ID:
Clone ID:
  • Human(1908) Summary: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(13616) endothelin 3
  • Rat(366270) endothelin 3
  • cow(513753) endothelin 3
  • naked mole-rat(101722729) endothelin 3
  • dog(403406) endothelin 3
  • chicken(768509) endothelin 3
  • Horse(100034064) endothelin 3
  • sheep(101114458) endothelin 3
  • domestic guinea pig(100733839) endothelin 3

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-EDN3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
western blot

Proteins

제품 번호
설명
Endothelin 3 human, rat, ≥97% (HPLC), powder,
human, rat

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Edn3,
mouse
MISSION® esiRNA, targeting human EDN3,
human