DUSP1
dual specificity phosphatase 1
동의어:
CL100, HVH1, MKP-1, MKP1, PTPN10
종:
Human DUSP1 (1843), Mouse Dusp1 (19252), Rat Dusp1 (114856), Domestic Rabbit DUSP1 (100340993), sheep DUSP1 (101107632), naked mole-rat Dusp1 (101701425), domestic guinea pig Dusp1 (100725668), chicken DUSP1 (374192), Zebrafish dusp1 (406340), dog DUSP1 (489117) ...더
UniProtKB ID:
Clone ID:
- Human(1843) Summary: The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. [provided by RefSeq, Jul 2008]
- Mouse(19252) dual specificity phosphatase 1
- Rat(114856) dual specificity phosphatase 1
- Domestic Rabbit(100340993) dual specificity phosphatase 1
- sheep(101107632) dual specificity phosphatase 1
- naked mole-rat(101701425) dual specificity phosphatase 1
- domestic guinea pig(100725668) dual specificity phosphatase 1
- chicken(374192) dual specificity phosphatase 1
- Zebrafish(406340) dual specificity phosphatase 1
- dog(489117) dual specificity phosphatase 1
- cow(539175) dual specificity phosphatase 1
- domestic cat(101093416) dual specificity phosphatase 1
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Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti Dual specificity phosphatase 1 Antibody, clone 23GB5760, Rabbit Monoclonal, clone 23GB5760, recombinant rabbit monoclonal, expressed in HEK293 cells,
종별 반응성
human, rat
응용분야
flow cytometry
western blot
western blot
Anti-MKP1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-DUSP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
western blot
western blot
Anti-phospho-MKP-1/2 (pSer296/318) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
western blot