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Merck

DRD4

dopamine receptor D4

동의어:
D4DR
종:
Human DRD4 (1815), Mouse Drd4 (13491), Rat Drd4 (25432), naked mole-rat Drd4 (101708437), dog DRD4 (448805), domestic guinea pig Drd4 (100733356), dog DRD4 (607223), chicken DRD4 (423016)
UniProtKB ID:
P21917, B0M0J7, Q7Z7Q5, Q8NGM5
Clone ID:
  • Human(1815) Summary: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
  • Mouse(13491) dopamine receptor D4
  • Rat(25432) dopamine receptor D4
  • naked mole-rat(101708437) dopamine receptor D4
  • dog(448805) dopamine receptor D4
  • domestic guinea pig(100733356) dopamine receptor D4
  • dog(607223) dopamine receptor D4
  • chicken(423016) dopamine receptor D4

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Small Molecule - Agonist

제품 번호
설명
종
P233
PD 168,077 maleate salt, powder,
종
human
Y0001465
Apomorphine hydrochloride hemihydrate, European Pharmacopoeia (EP) Reference Standard,
종
human
R2530
Ropinirole hydrochloride, powder, ≥98% (HPLC),
종
human
A1237
Pramipexole dihydrochloride, >98% (HPLC), powder,
종
human
1041008
Apomorphine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
종
human

Small Molecule - Antagonist

제품 번호
설명
종
U115
U-101958 maleate salt, solid,
종
human
L131
L-745,870 hydrochloride, ,
종
human
L135
L-741,626, ≥98% (HPLC),
종
human
31679
Chlorpromazine hydrochloride, VETRANAL®, analytical standard,
종
human
46674
Promazine hydrochloride, VETRANAL®, analytical standard,
종
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
HPA062682
Anti-Drd4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
AB1787P
Anti-Dopamine D4 Receptor Antibody, extracellular domain, Chemicon®, from rabbit,
종별 반응성
mouse
응용분야
ELISA
western blot
MABN125
Anti-DRD4 Antibody, clone 2B9, clone 2B9, from mouse,
종별 반응성
human, mouse, rat
응용분야
immunocytochemistry
western blot
324405
Anti-Dopamine D₄ Receptor Rabbit pAb, lyophilized, Calbiochem®,
종별 반응성
human, rat
응용분야

Small Molecule - Inhibitor

제품 번호
설명
종
D052
GBR 12909 dihydrochloride, solid, ≥98% (HPLC),
종
human
1031401
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
종
human
PHR1841
Amoxapine, Pharmaceutical Secondary Standard; Certified Reference Material,
종
human
A-123
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
종
human
P1793
Pimozide, ,
종
human, mouse, rat

Small Molecule - Metabolite

제품 번호
설명
종
M4251
3-Methoxytyramine hydrochloride, ≥95.5%, crystalline,
종
human
H3132
3-Hydroxy-4-methoxyphenethylamine hydrochloride, ,
종
human

Small Molecule - Mixed Agonist/Antagonist

제품 번호
설명
종
B9308
BP897, >98% (HPLC), solid,
종
human, rat
H1512
Haloperidol, powder,
종
human, rat
C6305
Clozapine, ,
종
human, rat

Small Molecule - Precursor

제품 번호
설명
종
D9503
3,4-Dihydroxy-DL-phenylalanine, ,
종
mouse, human, rat
D9628
3,4-Dihydroxy-L-phenylalanine, ≥98% (TLC),
종
mouse, human, rat

esiRNA

제품 번호
설명
종
EMU028911
MISSION® esiRNA, targeting mouse Drd4,
종
mouse