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Merck

DR1

down-regulator of transcription 1, TBP-binding (negative cofactor 2)

동의어:
NC2, NC2-BETA
:
UniProtKB ID:
Clone ID:
  • Human(1810) Summary: This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq, Jul 2008]
  • Mouse(13486) down-regulator of transcription 1
  • Rat(289881) down-regulator of transcription 1
  • Zebrafish(768171) down-regulator of transcription 1
  • chicken(424496) down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • cow(613828) down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • domestic cat(101098807) down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • dog(479943) down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • sheep(101105865) down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • naked mole-rat(101707064) down-regulator of transcription 1, TBP-binding (negative cofactor 2)
  • domestic guinea pig(100724062) down-regulator of transcription 1, TBP-binding (negative cofactor 2)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-DR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-DR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-DR1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
immunofluorescence
western blot

Proteins

제품 번호
설명
Dr1 (NC2β, 19 kDa), GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human DR1,
human
MISSION® esiRNA, targeting mouse Dr1,
mouse