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Merck

DNTT

DNA nucleotidylexotransferase

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TDT
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UniProtKB ID:
Clone ID:
  • Human(1791) Summary: This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
  • Mouse(21673) deoxynucleotidyltransferase, terminal
  • Rat(294051) DNA nucleotidylexotransferase
  • Horse(100061113) deoxynucleotidyltransferase, terminal
  • naked mole-rat(101718847) DNA nucleotidylexotransferase
  • dog(486815) deoxynucleotidyltransferase, terminal
  • sheep(101111504) deoxynucleotidyltransferase, terminal
  • chicken(396351) deoxynucleotidyltransferase, terminal
  • Domestic Rabbit(100353958) deoxynucleotidyltransferase, terminal
  • cow(281120) deoxynucleotidyltransferase, terminal
  • domestic cat(101097099) deoxynucleotidyltransferase, terminal
  • Zebrafish(544653) deoxynucleotidyltransferase, terminal
  • domestic guinea pig(100717998) DNA nucleotidylexotransferase

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Antibodies

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Anti-DNTT antibody produced in rabbit, Prestige Antibodiesยฎ Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
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human
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immunofluorescence
Anti-TdT/DNTT Antibody, clone 41A, ,
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human
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immunofluorescence
immunohistochemistry

western blot
Anti-Terminal deoxynucleotidyl transferase (TdT) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM379, purified immunoglobulin,
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human
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immunohistochemistry
western blot

esiRNA

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MISSIONยฎ esiRNA, targeting human DNTT,
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human