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Merck

DMP1

dentin matrix acidic phosphoprotein 1

동의어:
ARHP, ARHR, DMP-1
:
UniProtKB ID:
Clone ID:
  • Human(1758) Summary: Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13406) dentin matrix protein 1
  • Rat(25312) dentin matrix acidic phosphoprotein 1
  • Thale Cress(821706) DUF679 domain membrane protein 1
  • domestic guinea pig(100732102) dentin matrix acidic phosphoprotein 1
  • naked mole-rat(101725040) dentin matrix acidic phosphoprotein 1
  • sheep(100861441) dentin matrix acidic phosphoprotein 1
  • sheep(101123558) dentin matrix acidic phosphoprotein 1
  • domestic cat(101095652) dentin matrix acidic phosphoprotein 1
  • cow(281118) dentin matrix acidic phosphoprotein 1
  • chicken(404539) dentin matrix acidic phosphoprotein 1
  • dog(487849) dentin matrix acidic phosphoprotein 1

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ELISA

제품 번호
설명
Human DMP1 / Dentin Matrix Acidic Phosphoprotein 1 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-DMP1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-DMP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Anti-DMP-1 (CT) Antibody, clone 8G10.3, clone 8G10.3, from mouse,
종별 반응성
human, mouse, rat
응용분야
dot blot
immunohistochemistry

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human DMP1,
human