DCX
doublecortin
동의어:
DBCN, DC, LISX, SCLH, XLIS
종:
Human DCX (1641), Mouse Dcx (13193), Rat Dcx (84394), chicken DCX (374242), dog DCX (612950), domestic cat DCX (494212), cow DCX (787968), Horse DCX (100058909), sheep DCX (101109861), naked mole-rat Dcx (101711611)
UniProtKB ID:
Clone ID:
- Human(1641) Summary: This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
- Mouse(13193) doublecortin
- Rat(84394) doublecortin
- chicken(374242) doublecortin
- dog(612950) doublecortin
- domestic cat(494212) doublecortin
- cow(787968) doublecortin
- Horse(100058909) doublecortin
- sheep(101109861) doublecortin
- naked mole-rat(101711611) doublecortin
- domestic guinea pig(100713827) doublecortin
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
제품 번호
설명
종별 반응성
응용분야
Anti-Doublecortin antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
ELISA
western blot
western blot
Anti-DCX antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human, mouse, rat
응용분야
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-DCX (AB1) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
western blot
Anti-DCX (AB2) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
dog, horse, human, mouse, pig
응용분야
western blot
Anti-Doublecortin Antibody, clone 6H1B3, Rabbit Monoclonal, ,
종별 반응성
mouse, rat
응용분야
western blot
esiRNA
제품 번호
설명
종