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Merck

CYP2C9

cytochrome P450, family 2, subfamily C, polypeptide 9

동의어:
CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
:
UniProtKB ID:
Clone ID:
  • Human(1559) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-CYP2C9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
MONOCLONAL ANTI-CYP2C9 (N-TERMINAL) antibody produced in mouse, crude ascites, buffered aqueous solution,
종별 반응성
human
응용분야
western blot

Small Molecule - Inhibitor

제품 번호
설명
Thiabendazole, suitable for plant cell culture,
human
Thiabendazole, ≥99%, powder,
human
3,3′-Methylene-bis(4-hydroxycoumarin), ,
human
Sulfaphenazole, ≥98%,
human
Phenylbutazone, ,
human

Proteins

제품 번호
설명
Cytochrome P450 2C9*3 (I359L), human, recombinant, expressed in E. coli,
human
CypExpress 2C9 Cytochrome P450 human, ,
human
Cytochrome P450 2C9*2 (R144C), human, recombinant, expressed in E. coli,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CYP2C9,
human

Small Molecule - Substrate

제품 번호
설명
Tolbutamide, analytical standard,
human, mouse