CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B
- Human(1589) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- dog(415124) cytochrome P450c21
- cow(282425) cytochrome P450, family 21, subfamily A, polypeptide 2
- chicken(429828) cytochrome P450, family 21, subfamily A, polypeptide 2
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Antibodies
Anti-Cytochrome P450 21A2 antibody produced in rabbit, affinity isolated antibody,
human
ELISA
western blot
western blot
Anti-CYP21A2 (N-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
human
ELISA
western blot
western blot
Anti-CYP21A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
western blot
western blot
Anti-CYP21A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
western blot
western blot