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Merck

CYP17A1

cytochrome P450, family 17, subfamily A, polypeptide 1

동의어:
CPT7, CYP17, P450C17, S17AH
:
UniProtKB ID:
Clone ID:
  • Human(1586) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
  • Mouse(13074) cytochrome P450, family 17, subfamily a, polypeptide 1
  • Rat(25146) cytochrome P450, family 17, subfamily a, polypeptide 1
  • Horse(100034232) cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase
  • Zebrafish(399692) cytochrome P450, family 17, subfamily A, polypeptide 1
  • cow(281739) cytochrome P450, family 17, subfamily A, polypeptide 1
  • sheep(493968) cytochrome P450, family 17, subfamily A, polypeptide 1
  • domestic cat(493967) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(425056) cytochrome P450, family 17, subfamily A, polypeptide 1
  • dog(477807) cytochrome P450, family 17, subfamily A, polypeptide 1

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Cytochrome P450 17A1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
western blot
Anti-CYP17A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
western blot
Anti-CYP17A1 Antibody, clone 5D2H1, Rabbit Monoclonal, ,
종별 반응성
mouse
응용분야
immunofluorescence
western blot
Anti-CYP17A1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
canine, cat, human
응용분야
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

제품 번호
설명
Abiraterone acetate, United States Pharmacopeia (USP) Reference Standard,
human
Abiraterone acetate, ≥98% (HPLC),
human
(R)-(+)-Aminoglutethimide, 97%,
human
Galeterone, ≥98% (HPLC),
human
(S)-(−)-Aminoglutethimide, 97%,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human CYP17A1,
human
MISSION® esiRNA, targeting human CYP17A1-AS1,
human