콘텐츠로 건너뛰기
Merck

CYP11B1

cytochrome P450, family 11, subfamily B, polypeptide 1

동의어:
CPN1, CYP11B, FHI, P450C11
종:
Human CYP11B1 (1584), Mouse Cyp11b1 (110115), Rat Cyp11b1 (500892), sheep CYP11B1 (767576), cow CYP11B1 (282422), domestic guinea pig Cyp11b1 (100135511)
UniProtKB ID:
P15538, Q14095, Q4VAQ8, Q4VAQ9, Q9UML2
Clone ID:
  • Human(1584) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(110115) cytochrome P450, family 11, subfamily b, polypeptide 1
  • Rat(500892) cytochrome P450, family 11, subfamily b, polypeptide 1
  • sheep(767576) cytochrome P450, family 11, subfamily B, polypeptide 1
  • cow(282422) cytochrome P450, subfamily XI B, polypeptide 1
  • domestic guinea pig(100135511) cytochrome P450, family 11, subfamily b, polypeptide 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

제품 번호
설명
종별 반응성
응용분야
ZRB2564
Anti-CYP11B1 Antibody, clone 1J14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, monkey
응용분야
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
SAB1303151
ANTI-CYP11B1 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
종별 반응성
human
응용분야
flow cytometry
immunohistochemistry
western blot
HPA056348
Anti-CYP11B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
MAB6020
Anti-Cytochrome P450 11β-Hydroxylase Antibody, clone 11B2-1A4, culture supernatant, clone 11B2-1A4, Chemicon®,
종별 반응성
rat
응용분야
immunohistochemistry
western blot

Small Molecule - Inhibitor

제품 번호
설명
종
35485
2,4′-DDD, PESTANAL®, analytical standard,
종
human
1445007
Mitotane, United States Pharmacopeia (USP) Reference Standard,
종
human
44012
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
종
human
K1003
Ketoconazole, 99.0-101.0% (EP, titration),
종
mouse, human, rat

esiRNA

제품 번호
설명
종
EHU140441
MISSION® esiRNA, targeting human CYP11B1,
종
human